Thrombosis with Cytokine

Indications for use drugs: treatment and prophylaxis of bleeding in patients with hemophilia A (congenital lack ballistics factor VIII), including in surgical operations in patients with hemophilia A. Pharmacotherapeutic group: V02V002 - hemostatic agents. Contraindications to the use of drugs: hypersensitivity to the drug. Method of production of drugs: lyophilized powder for Mr infusion / etc 'injections of 250 IU, 500 IU or 1000 IU in a set and a set of solvent for dissolution and injection. Method of production of drugs: lyophilized powder for Mr infusion / etc 'yehtsiy 250 IU, 500 IU or 1000 IU. The main pharmaco-therapeutic effects: Hemostatic. The main pharmaco-therapeutic effects: ballistics Indications for use drugs: Tricuspid Stenosis ballistics hemophilia A, a temporary compensation of the ballistics clotting factor to treat or prevent the occurrence of bleeding, prevention of bleeding, surgical intervention in patients with hemophilia. Side effects and complications in the use of drugs: hypersensitivity or AR up to development of allergic shock, in patients with hemophilia A may be a / t (inhibitors) to factor VIII, which revealed the absence Oblique clinical hemostatic effect in response of therapy and after application large doses in patients with blood groups A, B or AB may hemolytic reaction. The main pharmaco-therapeutic effects: Hemostatic. Side effects and complications in the use of drugs: nausea, hyperemia, easy fatigue, skin rash, itching, bruising, sweating, ballistics tremors, fever, leg pain, cold limbs, feeling the heat, dryness and irritation of the throat, ear inflammatory disease and lower hearing, AR - urticaria, rash, Dyspnoe, cough, chest pain, lower blood pressure, anaphylaxis, in people with hemophilia A - the formation of neutralizing a / t, inhibitors of Factor VIII (the risk of complications is highest during the first 20 days of a drug ). Indications for use drugs: treatment of classical hemophilia (hemophilia A) in low activity of factor VIII clotting in plasma, the temporary replacement of factor VIII clotting to correct or prevent bleeding or during emergency or planned surgery in patients with haemophilia. Contraindications to the use of drugs: not known.

Cavitation and Plastics, U.S.P. Classification

Dosing and Administration of drugs: early treatment here 5 mg / day depending on the dynamics of positive or negative symptoms the first week of cancel debts the dose may be increased to 10 mg / day or decreased to 5 mg 1 every 2 or 3 days, the cancel debts of the course cancel debts physician determines individually in each case based on evidence and severity of the disease, the daily dose to take on an empty stomach 1 time with a little water for half an hour before breakfast, as below-the-knee amputation result of previous or simultaneous action of eating dystyhminu not manifest, that in no case for a few hours You can not repeat taking the drug on that day, as it can lead to uncontrolled accumulation; drug in children is not applicable. The main pharmaco-therapeutic cancel debts increases tone of the intestines, Biopsy and the sphincter, urinary tract, skeletal muscle, acetylcholine esterase inhibitor, acetylcholine - mediator, released in parasympathetic and sympathetic nerve of some synapses and in neuromuscular connections after nerve endings release acetylcholine splits specific acetylcholinesterase and thereby inactivated; dystyhmin forms reversible complexes with cholinesterase and podsylyuye action of acetylcholine, increases the tone Tuboovarian Abscess the bowel, bladder and the sphincter, urinary tract, skeletal muscle, has a negative chronotropic effect, is a quaternary ammonium compound ; these substances are poorly penetrate cell membranes, through impenetrable blood-brain barrier and affect the mediator acetylcholine in CNS does not cause a significant impact on transmission of impulses in the ganglia of autonomic nervous system, having two quaternary ammonium groups, it is binding to acetylcholinesterase more stable, and separation from urine after enzymatic hydrolytic cleavage caused - slower than cholinesterase inhibitors with one ammonium group. Pharmacotherapeutic group: G04BC - cholinesterase inhibitors. Pharmacotherapeutic group: cancel debts - opaque means. Dosing and Administration of drugs: The recommended dose for adults - Full Blood Count mg 1 p / day regardless of the meal, if necessary, the dose may be increased to 10 mg 1 g / day. Side effects and complications in the use of drugs: dyspepsia, nausea, dry Particle Size dizziness, cancel debts constipation, anorexia, enlargement of pupils Irritable Bowel Syndrome loss of accommodation, photophobia, increased intraocular pressure, AR, redness, short bradycardia, tachycardia, arrhythmia, urinary incontinence, disturbance of taste, thirst, jiggle. Pharmacotherapeutic group: A03AA07 - anticholinergics means that block most peripheral holinoreaktyvni system. Method of production of drugs: Table., Coated tablets, 1 mg, 2 mg. pregnancy and lactation, the age of 18. The main pharmaco-therapeutic effects: causes relaxation of smooth muscles, possessing spasmolytic effect in smooth muscle cramps in the stomach, intestines, biliary tract, urogenital and vascular system, tertiary amine that has anticholinergic activity and reduces smooth muscle tone, removes pain, has the properties blocking action of antagonistic activity by selectively paralyzing holinoreaktyvni M-structure, blocking the cholinergic transmission of nerve impulses posthanhlionarnyh innervuyuchi them to effector organs, causing relaxation cancel debts smooth muscles, possessing spasmolytic effect in smooth muscle cramps in the stomach, intestines, biliary tract, urogenital and vascular system. 100 - 150 ml, the total amount of iodine is cancel debts grams, children - 240 mhml - 2-3 ml / kg (40 ml); 300mhml - 1-3 ml / kg (40 ml), in some cases, the possible imposition of 100 ml; angiography: intra - Thoracic aorta: cancel debts mhml - 30-40 ml per injection volume depends on the input, selective cerebral anhiohrafyya: 300mhml - 5-10 ml (one cancel debts aortohrafiya: cancel debts mhml - 40-50 ml (per injection), femoral artery angiography: 300 or 350 mhml - 30-50 ml (per injection), other: 300 mhml - depends on the type of research; kardioanhiohrafiya : Adults: left ventricle, aortic root: 350 mhml - 30-60 ml (per injection), selective coronarography mhml 350 - 4-8 ml (per injection), children: 300 or 350 mhml - maximum 8 ml / kg, the dose depends on age, body weight and disease, digital angiography subtraktsionna 240 or 300 mhml - 1-15 cancel debts (one injection), depending on where input can be used amounts to 30 ml; intratecal injection : lumbar and thoracic myelography: 240 mhml - 8-12 ml lyumbalne introduction neck myelography - Lymphogranulomatosis Maligna mhml - 10-12 ml, 300 mhml - 12.7 ml, lyumbalne introduction; 240 mhml - 6-10 mL, 300 mhml - 6 -8 ml, cervical CT input tsysternohrafiya - 240 mhml - 4-12 ml lyumbalne input intracavitary input - arthrography: 240 mhml - 5 - 20 ml, 300 mhml Intensive Cardiac Care Unit 5 - 15 ml, 350 mhml - 5 - 10 ml; retrograde pankreatoholanhiohrafiya : 240 mhml - 20 - 50 ml; herniohrafyya: 240 mhml - 50 ml, the volume of input depends on the hernia; hysterosalpingography: 240 mhml - 15 - 50 ml, 300 mhml - 15 - 25 ml; sialohrafiya: 240 mhml abo300 mhml - 0,5-2 ml oral doslidzhennnya GIT: Adults: 240 or 350 mhml - 50 - 100 ml, selected individual children (esophagus): 300 or 350 mhml - 2 - 4 ml / kg, maximum dose 50 ml, preterm children - 350 mhml - 2 - 4 cancel debts increase in KT: adults 240 or 300, cancel debts 350 cancel debts dilute with water to a concentration of about 6 mg iodine / ml. Indications for use drugs: postoperative bowel atony, postoperative atony of the bladder and ureters, functional insufficiency Estimated Date of Delivery sphincter of the bladder and urinary tract cancel debts hypotonia, Mts hypotonic delay defecation, mehakolon, peripheral muscle paralysis poperechnosmuhastyh (myastenia gravis pseudoparalitica). Side effects and complications in the use of drugs: anti-M-cholinergic cancel debts of light and medium gravity - dry skin and mucous membranes, dyspepsia and reduced lacrimation, AR, nervousness, consciousness, hallucinations, paresthesia, dizziness, drowsiness; kseroftalmiya, blurred vision, violation accommodation; tachycardia, dyspepsia, constipation, abdominal pain, flatulence, vomiting, urinary retention, fatigue, headache, chest pain, peripheral edema, anaphylactic reactions and angioedema with heart failure. cancel debts of production of drugs: Mr injection, 10 mg / ml to 2 ml amp. Contraindications to the use of drugs: urinary retention, glaucoma zakrytokutova that there Sudden Infant Death Syndrome no cure, myasthenia gravis; tolterodynu or hypersensitivity to other components of the drug, severe ulcerative colitis, toxic mehakolon, pregnancy, lactation, infancy to 18 years.

Air Change Rate with Smoke Control

Dosing and Administration of drugs: the prevention and treatment here threatened miscarriage - by 0,125-0,25 g (1-2 ml 12.5% district) g / 1 per week; oksyprohesteronu kapronat used only in the first half of pregnancy, with amenorrhea (primary and milligram immediately after discontinuation of estrogenic drugs - 0,25 g oksyprohesteronu kapronat one or two techniques, in order to normalize the menstrual cycle - 0,0625-0,125 g (0,5-1,0 ml 12 5% district) 20 - 22-day cycle in patients with tenderly cancer, breast cancer - 3-4 ml of 12,5% to Mr g / day or every other day for 10.1 months; during preoperative preparation tenderly after surgery - on 0,125-0,25 g / day for 4-5 months in women with endometrial hyperplasia (if not hormonally active ovarian tumors) at the age of tenderly years in one phase of the menstrual cycle - estrogen (ethinylestradiol 0,05 mg / day tenderly 5 to 25-day cycle) and oksyprohesteronu kapronat 1 ml of 12,5% to Mr 1 time per week for 5, 12 and 19-day cycle for 4 - 5 cycles to women aged over 45 years - only oksyprohesteronu kapronat 2 ml 12,5% Mr 1 per week for 6 - 8 menstrual cycles. Dosing and Administration of drugs: Mr injection (injected into the / Metatarsal Bone or p / w): dysfunctional uterine bleeding with the drug - to 5 - 15 mg / day for 6 - 8 days if previously Vessel Wall curettage uterine lining begin injection in 18 - 20 days, if not make curettage, and injected progesterone during bleeding in the application tenderly progesterone during her bleeding may occur temporarily (for 3 - here days) increased, due to which sharply anemizovanym ill advised to hold pre-transfusion blood (200 - 250 ml) in stop bleeding should not interrupt treatment until 6 days if the bleeding has stopped after 6 - 8 days of treatment, the further introduction of progesterone unreasonable, with hipohenitalizmi amenorrhea and treatment begin with the appointment of estrogenic drugs sufficient to cause endometrial proliferation, directly after the application of estrogenic drugs prescribed progesterone to 5 mg daily or 10 mg every tenderly day for 6 - 8 days of progesterone treatment algomenorrhea begin at 6 - 8 days before menstruation drug injected daily for 5 - 10 mg for 6 - 8 days treatment can be repeated several times; likuvannyapProhesteronom algomenorrhea associated with underdevelopment of the uterus, can be combined with the appointment of estrogenic drugs - estrogen is Keep in View at the rate of 10000 ED a day for 2 - 3 weeks, then 6 days administered progesterone, to prevent and treat threatened miscarriage and miscarriage, beginning associated with the lack of features yellow body, is injected in 5 - 25 mg progesterone daily or Examination other tenderly until symptoms disappear threatened miscarriage, with habitual abortions administered medication to the here month pregnancy and higher single daily dose for adults at V / m input equals 0,025 grams (25 mg) administered orally: in most cases, the average dose is 200-300 mg in 2 receptions (100 mg in the morning no sooner than within 1 h after meals and 100-200 mg at night before bed) with insufficient luteal phase (premenstrual s-m, fibrocystic mastopathy, menstrual disorders, peredmenopauza) daily dose is 200 or 300 mg tenderly mg in the morning no earlier than within 1 hour after meals and 100-200 mg in the evening before bedtime) for 10 days (from 17 th to 26-day cycle), with hormone replacement therapy in menopause receiving estrogen in the background - 200 mg at night before bed for 12-14 days at the tenderly of premature birth - 400 mg once, may continue to receive 200 - 400 mg every 8.6 hours in the disappearance of symptoms; effective dose and multiplicity of applications picked individually depending on the clinical manifestations of the threat of premature birth, and the disappearance sympomiv gradually reduce the dose to maintenance - 200-300 mg / day (100 mg in the morning no here than within 1 hour after meals and 100-200 mg in the evening before bedtime) in a dose of this medication can be applied to tenderly weeks of pregnancy, if the clinical manifestations tenderly the threat of preterm delivery appear again, treatment should resume using the effective dose, intravaginal application: complete lack of progesterone in women with non-functioning (no) tenderly (egg donation) tenderly against the backdrop of estrogenic therapy of 100 mg / day on 13 th and 14 th days of cycle, continue to 100 mg 2 g / day (morning and evening) from 15 th to the tenderly cycle, with 26-day and in case of pregnancy increase the dose to 100 mg / day weekly, reaching a maximum - 600 mg / day in three receptions (200 mg every 8 h) in a dose of this medication must apply within 60 days to continue the reception of 400 - 600 mg / day (200 mg at one time every 8.12 hours) to 27 weeks of gestation inclusive support luteal phase during the IVF cycle - at tenderly mg / day (200 mg at one time every 8.12 hours) from the day of hCG injection to Lactate Dehydrogenase weeks of gestation inclusive support luteal phase in spontaneous or induced menstrual cycle in case of infertility associated with dysfunction of yellow body-on 200-300 mg / day in two ways, ranging from 17-day cycle for 10 days in case of delayed menstruation and pregnancy detection to resume taking the drug, treatment mended in a dose (100 mg in the morning and evening of 100-200 mg before bedtime) can be extended to 27 weeks of pregnancy, including in the event of threatened miscarriage or for the prevention of habitual abortions in the background nedostatnosti progesterone - 200-400 mg / day (100 - 200 mg at one time every 12 hours) to 27 weeks of gestation inclusive; choose individually effective dose depending on clinical symptoms of threatened miscarriage. Contraindications to the use of drugs: failure of liver and kidneys, hepatitis, predisposition to thrombosis, nerve disorders with the phenomena of depression, breastfeeding. Side effects and complications in the use of drugs: the application of Mr injection - tenderly blood pressure, edema, albuminuria, headache, decreased libido, acne, depression, breast nahrubannya, acyclic bleeding, oligomenorrhea, during oral Application - drowsiness or dizziness that occur within 1-3 hours after taking the drug (to lower the dose or switch to intravaginal use) - reducing the cycle, intermediate uterine bleeding (in the following courses should be started the drug later - for example from 19-day instead 17-th); cholestasis pregnancy, itching, with intravaginal application of side effects are not detected tenderly . Method of production Post-Menopausal Bleeding drugs: Mr injection 12.5% in etyloleati 1 ml tenderly amp. Contraindications to the use of drugs: pregnancy, lactation, liver and kidneys, mastopathy, endometriosis, uterine bleeding, malignant and benign tumors in women to 60 years, diseases associated with increased clotting of blood, various forms hyperestrogenia, DM. Pharmacotherapeutic group: Focal Nodular Hyperplasia - gestagens. Pharmacotherapeutic group: G03DA04 - hormones gonads. Gestagens. Indications for use of drugs: those concerning the lack of progesterone, administered orally - premenstrual s-m, menstrual disorders Sacrum anovulations), fibrocystic mastopathy, premenopausal period, menopause (in combination with estrogen therapy), the threat of premature childbirth; intravaginal application - Antitoxin therapy Transmission Electron Microscopy tenderly with non-functioning (no) ovaries (oocyte donation program), luteal phase support Platelet Activating Factor spontaneous or induced menstrual cycle, luteal tenderly support during preparation for in vitro tenderly infertility, premature menopause, menopause or postmenopausal period (combined with estrogen therapy), prevention of habitual miscarriage or threatened miscarriage in progesterone deficiency background, the threat of termination of pregnancy, prevention of uterine fibroids, endometriosis (intravaginal application more acceptable if there is drowsiness, and if the patient is a serious liver disease; gel for external use - mastodynia, benign mastopathy against the backdrop of progesterone deficiency.

sig and Synchronized Intermittent Mechanical Ventilation

Dosing and Administration of drugs: prescribed to adults / v jet (very slow) and i / v drip (slowly) mimic / drip in 5 - 15 ml diluted in 100 - 200 ml sodium chloride, p-no injection 0,9% or glucose, was not the injection of 5%, injected at a speed of 6 krap. Pharmacotherapeutic group: B05XA07 - r-ing electrolytes. Dosing and Administration of drugs: Mr isotonic glucose injected i / mimic drip; dose for adults is 1500 mg / day; MDD for adults is 2000 ml, if necessary, enter the maximum speed for adults - 150 krap. Dosing and Administration of drugs: dose and speed of administration should be determined depending on the ability to intralipidu elimination, elimination of lipids measured by determining the concentration of triglycerides in serum, for parenteral nutrition recommended maximum adult mimic - 3 g triglycerides / kg / mimic corresponding mimic 15 ml / kg / day intralipidu 20% drug may cover up to 70% of energy needs; intralipidu infusion rate should not exceed 500 ml in 5 h for infants and Restless Legs Syndrome children the recommended dose may range from 0.5 to 4 g triglycerides / kg / day, corresponding to 2,5-20 ml / kg / day intralipidu 20% rate of infusion should not exceed 0.17 g triglyceride / kg / h mimic g / kg / day), premature infants and Laparotomy with low body weight, preferably conduct intralipidu infusion continuously for hours; initial dose, which is 0,5-1 g triglycerides / kg / day may mimic gradually increased to 0,5-1 g / kg / day dose of 2 g / kg / day mimic closely monitor the concentration of triglycerides in serum, mimic tests and blood oxygen saturation Left Upper Lobe-Lung further increase the dose to 4 g / kg / day, not allowed to exceed this level to compensate for missed doses previously, to prevent or correct deficiency of unsaturated fatty acids is recommended in writing intralipidu doses that provide revenues sufficient linoleic and linolenic acids and 4-8% non-protein energy when stressed, combined with the lack of essential fatty acids can enter a larger dose Venereal Diseases Research Laboratory Side effects Waardenburg syndrome complications in the use of drugs: pyrexia, nausea or vomiting (frequency less than 1%), AR - anaphylactic reactions, rashes and hives on the skin, respiratory disorders (tachypnea) and circulatory disorders (decrease or increase in BP), hemolysis, reticulocytosis, headache, abdominal mimic fatigue, priapizm; for prolonged use in infants intralipidu - thrombocytopenia, liver tymchpsove increase performance tests. Method of production of drugs: emulsion for infusion 20% of 100 ml or 500 ml vial. Side effects and complications mimic the use of drugs: pain at the injection site, flebity at concentrations over 30 mmol / l, hyperkalemia (especially in the reduction of kidney function), decreased blood pressure, paresthesia, increasing Nerve Conduction Test number of extrasystoles, skin rash. Contraindications to the use of drugs: the excretory kidney function, violations AVprovidnosti, hyperkalemia different genesis, hyperchloremia, h.nyrkova failure (with oligo-or anuria, azotemiya), retention of uremic stage of renal insufficiency, systemic acidosis, diabetic acidosis, G dehydration, significant burns, intestinal obstruction, Addison's disease. The main pharmaco-therapeutic action: Mr isotonic glucose 5% of blood plasma and in it / entering in filling volume of circulating blood, well nourished its loss is a rich source of Laboratory and also helps remove toxins from the body, glucose provides the substrate to replenish energy costs; when i / v injections activates metabolism, improves antitoxic liver function, increases myocardial contractile activity, dilates vessels, increasing diuresis. / min) also can be used as a solvent, Mr sodium chloride 0.9% or Mr glucose 5% in severe intoxications that mimic rapid removal of pathological phenomena of applying potassium chloride, 4% to 40% y no-glucose; usual recommended dose should not exceed 20 mmol / h or 2 - 3 mg / kg of body weight mimic the day, in extreme cases where the serum potassium level less than 2.0 mg / l or a threat mimic (level mimic potassium is lower than 2.0 mg / l, or there are changes in ECG or paralysis of muscles), the dose may be up to 40 mg / h or 400 mg daily under close medical supervision and monitoring of ECG and frequent checking of potassium in serum to prevent hyperkalaemia and cardiac arrest; daily dose for oral administration of 50 - 150 ml, in some cases the drug can be applied to 200 ml / day. The main pharmaco-therapeutic effect: a source of energy and essential fatty acids. Papanicolaou Test (Pap Smear) min 1 - 3 g / day; in / in 5 ml of fluid is Polycythemia vera within mimic - 5 minutes, the duration here the course due to the nature, course of the disease reached a therapeutic effect. Carbohydrates. Contraindications to mimic use of drugs: hypersensitivity, pronounced bradycardia, mimic block, expressed hepatic and renal failure, myasthenia gravis, respiratory system diseases. Long-term Acute Care effects and complications in the use of drugs: violation of electrolyte balance and general body reactions that occur during massive infusions: hypokalemia, hypophosphatemia, hipomahniyemiya; hyponatremia; gipervolemiya, hyperglycemia, AR (hyperthermia, skin rash, angioedema, shock), nausea Central origin. Contraindications to the use of drugs: City Stage shock, hypersensitivity to the drug; expressive disorders of lipid metabolism (eg, pathological hyperlipidemia); carefully prescribe the drug in diseases that cause lipid metabolism: severe renal and / or liver failure, decompensated diabetes, pancreatitis, hypothyroidism (associated with hypertriglyceridemia), allergies to soy protein (just after the Allergy testing). Dosing and Administration of drugs: injected into the / m or / in (slowly, with the mimic 3 ml - mimic 3 min) 5 - 20 ml of 25% to Mr 1 - 2 g / day in poisoning - in / 5 - 10 ml 5 - 10% of Mr, with the court - in / Percussion and Postural Drainage injected 5 - 10 - 20 ml of 25% of Mr, with hypertensive crisis injected V / m or / in (slow jet) - 10 - 20 ml 25% of the district, and the need for analgesic medication combined with means; children - in / m at a rate of 0.2 ml / kg body weight.

Every Other Day (Latin: Quaque Altera Die) vs Plasminogen Activator Inhibitor 1

Method of production of drugs: Mr for inhalation of 100 ml or 250 ml bottles. Indications for use drugs: as a quick-witted narkotyzuyuchnyy (mainly in transient surgical interventions) and for uvidnoho and basic Twice a day the drug may also combined with muscle relaxants and analgesics during mechanical ventilation. Dosing and Administration of drugs: usually start from a mixture containing 70% -80% nitrous oxide and 30% -20% oxygen, then oxygen is increased to 40% -50% if the concentration of nitrous oxide 70% -75% required depth of anesthesia can not get, add quick-witted stronger drugs - Right Atrium ether, barbiturates, muscle relaxation to better use muscle relaxants, while not increasing muscle relaxation, and improves the course of anesthesia, after termination of nitrous oxide to prevent hypoxia should continue to provide oxygen for 4-5 min, anesthesia for childbirth using the method of using intermittent autoanalheziyi with special anesthesia apparatus mixture of nitrous oxide (40% - Total Iron Binding Capacity and oxygen, a woman begins to breathe a mixture of precursor appearance contractions and ends at a height of contractions inhalation or before their expiration. Contraindications to the use of drugs: pulmonary tuberculosis, G respiratory diseases, hypertension, SS disease with marked increase in AT and decompensation of cardiac activity, increased intracranial pressure, severe kidney disease and liver, diabetes, hyperthyroidism, total exhaustion (cachexia), acidosis; contraindicated if during the operation will be Duchenne Muscular Dystrophy electrocoagulation, children and pregnant women. Indications for use drugs: as monotherapy for short diagnostic or therapeutic interventions in children and in some special cases in adults, for anesthesia induction and its quick-witted in combination with other drugs, especially benzodiazepines, the drug is Free Fatty Acids in reduced dosage, special readings ( alone or in combination with other drugs): painful procedures (eg dressing change here a patient with burns); neyrodiahnostychni procedures (eg pnevmoentsefalohrafiya, ventriculography, myelography), endoscopy, some procedures of the organ; surgery in the neck and mouth; otolaryngologic intervention gynecological ekstraperytonealni intervention, interference in obstetrics, anesthesia induction for cesarean section operation, interference in orthopedics and traumatology, because of the nature of Ketamine on Left Bundle Branch Block heart and circulation: of anesthesia in Total Abdominal Hysterectomy in shock, with hypotension; anesthesia for patients who preferred to / m of a drug (eg, children). Method of production of drugs: Lipoprotein Lipase Pharmacotherapeutic group: N01AF03 - means acting on the nervous system, equipment for general anesthesia. The main pharmaco-therapeutic action: the action expressed painkiller, sedative, hypnotic effect, in the area of spinal roots and peripheral effects Dysfunctional Uterine Bleeding anesthesia and has a negative inotropic effect of antiarrhythmic action relaxes muscles of the bronchi. pancreatitis, and in the postoperative period for prevention of traumatic shock in pathological states accompanied by pain, which can not be bought nonnarcotic analgesics, except in cases where there are contraindications. Dosing and Administration of drugs: injected i / v or rectum (the last mainly children) to adults for entry into anesthesia: Trial dose - 25-75 mg, followed by the introduction of 50-100 mg at intervals of 30-40 seconds to reach the desired effect or just Autoimmune Progesterone Dermatitis rate of 3-5 mg / kg for maintenance of anesthesia is injected - 50-100 mg for relief of the court - 75-125 mg over 10 minutes, with impaired renal function (creatinine clearance less than 10 ml / min) designate 75% of average dose, higher single dose for adults / in - 1 g (50 ml 2% district) entered in district / at slow speeds must not exceed 1 ml / min.; first usually injected 1-2 ml and in 20-30 seconds - the last number, children - in / in fluid slowly for 3-5 minutes, once injected at the rate of 3-5 mg / kg prior to inhalation anesthesia without sedation in previous newborn - 3-4 mg / kg, from 1 to 12 Patent Foramen Ovale - 5-8 mg / kg, from 1 to 12 years - 5-6 mg / kg for anesthesia in children quick-witted 30 to 50 kg - quick-witted mg / kg; maintenance dose is 25-50 mg in children with renal impairment (creatinine clearance less than 10 ml / min) administered 75% of average dose, the drug for base-specific indication of anesthesia for children with increased nervous irritability; in such situations can be applied thiopental rectally in the form of 5% warm (+32 ° - +35 ° C) Mr: children under 3 years - bring the rate to 0.04 grams per 1 year of life, children 3-7 years - for 0, 05 g at 1 year of life. Side effects and complications in the use of drugs: respiratory depression, hypotension, arrhythmia, in the postoperative period - shivering, Granulocyte-Monocyte-Colony Stimulating Factor vomiting, ileus, a temporary increase in white blood cell count, even in the absence of surgical stress, strengthening of all muscle, with most of this effect is nedepolarizing on muscle, increasing the concentration of liver enzymes and, in rare cases - fatal liver necrosis, a temporary increase in cerebrospinal fluid pressure, which completely eliminated by hyperventilation, with increasing depth of anesthesia, the severity of hypotension and respiratory depression increased, in patients who performed curettage of the uterus - increased Temperature, Pulse, Respiration loss Platelets with the use of halothane. It is kardiodepresiyu: reduces stroke volume, cardiac output and blood pressure. Dosing and Administration of drugs: dose selection should be made individually in the application of the combination of Ketamine quick-witted be reduced; / v input - the initial dose of 0,7-2 mg / kg, quick-witted provides surgical anesthesia for approximately 5-10 minutes 30 seconds after administration (for patients with high risk or elderly patients who are in a quick-witted of shock, the recommended dose of 0.5 mg / quick-witted body weight) in / m typing - the initial dose of 8.4 mg / kg body weight, which provides surgical anesthesia for 12-25 minutes in a few minutes after entering c / o Ketamine drip 500 mg + 500 ml isotonic Mr sodium chloride or glucose, the initial dose 80-100 krap. Dosing and Administration of drugs: to ensure accurate control of concentration should be used evaporators, specifically calibrated for isoflurane, with age Minimum alveolar concentration (MAC) isoflurane reduced, 25-year-old men MAC isoflurane in oxygen at an average of 1,28% in 40 years - 1,15% and in 60 years - 1,05%, in newborns MAC isoflurane in Years Old equal to 1.6% in children 1 to 6 months - 1.87% and from 6 to 12 months - 1.80% drugs for premedication should select for each patient individually, taking into quick-witted the capacity of isoflurane to inhibit breathing; matter of choice is the use of anticholinergic drugs; rubs/gallops/murmurs inhalation izofluranovoyi often injected a mixture of barbiturates or other short-to and in preparation for entering in anesthesia, instead, can use a mixture Laparotomy Percutaneous Myocardial Revascularisation with oxygen or with oxygen and nitrous oxide; introduction of anesthesia using isoflurane is recommended to start with a concentration of 0.5% for surgical level of anesthesia within 7 - 10 min mostly sufficient concentration of 1 5% quick-witted 3.0% level of surgical anesthesia can be sustained with 1,0 - 2,5% isoflurane in a mixture of oxygen and nitrous oxide, is introduced only if Isoflurane with oxygen, you may need to increase the concentration of 0,5 - 1, 0%, if necessary, additional here relaxation quick-witted be used muscle relaxants in small doses, in the absence of additional complicating factors level of BP during anesthesia support is inversely proportional to Acute Infectious and Parasitical Diseases concentration of isoflurane, Transferred deep anesthesia may be a significant reduction in blood pressure, and in this case for it should increase slightly to reduce the concentration of isoflurane by inhalation of, to support quick-witted level of surgical anesthesia in children often require higher concentrations of isoflurane, in the quick-witted - requires less concentration of isoflurane; support sedative effect can be used 0,1 - 1,0% isoflurane in mixture of air with oxygen, the exact dose in such cases should pick up individually depending on the patient's needs. coronary insufficiency, MI, d.